Protein Alignment iotaTry and PRSS41

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001382429.1
• Gene: PRSS41 / 360226
• HGNCID: 30715
• Length: 334
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 78/277 - (28%)
• Similarity: 113/277 - (40%)
• Gaps: 82/277 - (29%)

  Fly    23 EATGR------IIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHCLHERSVTLMKVR 81
            ||.|.      :.||.:......|||.|:::..||.|||.:.|:..:::|.||.
Human    60 EACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCF----------- 113

  Fly    82 VGAQNHNYGG---------TLVPV--------AAYKVHEQFDS----RFLHYDIAVLRLSTPLTF 125
               |.|.|..         |..|.        :.|||.:...:    ..|..|||:|||::.:|:
Human   114 ---QKHYYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTY 175

  Fly   126 GLSTRAINLASTS------PSGGTTVTVTGWGHTDNGALSDS---------LQKAQLQIIDRGEC 175
            ....:.|.:.|::      |.    ..||||     |.:|.|         |::||:.|::...|
Human   176 NAYIQPICIESSTFNFVHRPD----CWVTGW-----GLISPSGTPLPPPYNLREAQVTILNNTRC 231

  Fly   176 ASQKFGY------GADFVGEETICAASTD--ADACTGDSGGPLVASSQ----LVGIVSWGYRCAD 228
                 .|      ....:.:...||.:.|  .|.|.||||||||....    .|||||||..|..
Human   232 -----NYLFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQ 291

  Fly   229 DNYPGVYADVAILRPWI 245
            .|.||||.::::...||
Human   292 PNRPGVYTNISVYFHWI 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	73/271 (27%)
PRSS41	NP_001382429.1	Tryp_SPc	71..311	CDD:238113	75/266 (28%)