DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment iotaTry and Prss53

DIOPT Version :9

Sequence 1:	NP_523695.1	Gene:	iotaTry / 36223	FlyBaseID:	FBgn0015001	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	235	Identity:	61/235 - (25%)
Similarity:	103/235 - (43%)	Gaps:	44/235 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PWQVSIQISARHECGGVIYSKEIIITAGHC--------LHERSVTLMKVRVGAQNHNYGGTLVPV 96
            |||.|::....|.|.|.:.:...::||.||        |...||.|..::...|:.  |...|.|
Mouse    49 PWQASVRRQGVHICSGSLVADTWVLTAAHCFEKMATAELSSWSVVLGSLKQEGQSP--GAEEVGV 111

  Fly    97 AAYKVHEQFDSRFLHY----DIAVLRLSTPLTFGLSTRAINLASTSPS----GGTTVTVTGWGHT 153
            ||.::.:.::    ||    |:|:|:|:.|      |....|....|:    .|.:...|||..
Mouse   112 AALQLPKAYN----HYSQGSDLALLQLTHP------TVQTTLCLPQPTYHFPFGASCWATGWDQ- 165

  Fly   154 DNGALSDSLQKAQLQIIDRGEC------ASQKFGYGADFVGEETICAASTDAD--ACTGDSGGPL 210
            :...:|.:|:..:|::|.|..|      ..|:........|  .:|..:...:  .|.||||||:
Mouse   166 NTSDVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPG--MLCGGAQPGEQGPCQGDSGGPV 228

  Fly   211 VASSQ-----LVGIVSWGYRCADDNYPGVYADVAILRPWI 245
            :....     .|||:|:..:||.::.|.:..|:|:...|:
Mouse   229 MCREPDGHWVQVGIISFTSKCAQEDTPVLLTDMAVHSSWL 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	60/233 (26%)
iotaTry	NP_523695.1	Tryp_SPc	28..247	CDD:238113	61/235 (26%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113	61/235 (26%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839503
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030