DRSC/TRiP Functional Genomics Resources

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Protein Alignment iotaTry and KLK9

DIOPT Version :9

Sequence 1:NP_523695.1 Gene:iotaTry / 36223 FlyBaseID:FBgn0015001 Length:252 Species:Drosophila melanogaster
Sequence 2:NP_036447.1 Gene:KLK9 / 284366 HGNCID:6370 Length:250 Species:Homo sapiens


Alignment Length:259 Identity:74/259 - (28%)
Similarity:112/259 - (43%) Gaps:36/259 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 GIVATVLVLLLLGDASDVEATGRIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHC 69
            |::..:|.||    |....|..|.||..:....:.|||..:....|..||..:.|...::||.||
Human     4 GLLCALLSLL----AGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHC 64

  Fly    70 LHERSVTLMKVRVGAQNH--NYGG--TLVPVAAYKVHEQFDSRFL----HYDIAVLRLSTPLTFG 126
               |...|. ||:| ::|  .:.|  .|..|..:..|..|:....    :.||.::||.......
Human    65 ---RKPYLW-VRLG-EHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLS 124

  Fly   127 LSTRAINLASTSPSGGTTVTVTGWGHTDNGALSD-------SLQKAQLQIIDRGECASQKFGYGA 184
            .:.:.:||:.|..|.|....::||     ||:|.       :||.|.:.|::...|.....|:  
Human   125 PAVQPLNLSQTCVSPGMQCLISGW-----GAVSSPKALFPVTLQCANISILENKLCHWAYPGH-- 182

  Fly   185 DFVGEETICAASTDA--DACTGDSGGPLVASSQLVGIVSWGYR-CADDNYPGVYADVAILRPWI 245
              :.:..:||...:.  .:|.||||||||.:..|.|:||.|.. |:....|.||..|.....||
Human   183 --ISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWI 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
iotaTryNP_523695.1 Tryp_SPc 27..245 CDD:214473 66/235 (28%)
Tryp_SPc 28..247 CDD:238113 67/236 (28%)
KLK9NP_036447.1 Tryp_SPc 24..247 CDD:238113 67/235 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

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