Protein Alignment iotaTry and PRSS33

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_690851.2
• Gene: PRSS33 / 260429
• HGNCID: 30405
• Length: 280
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 94/271 - (34%)
• Similarity: 124/271 - (45%)
• Gaps: 40/271 - (14%)

  Fly    10 VLVLLLLGDA----------SDVEATGRIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIII 64
            ||:||:||.|          .....:.||:||.|......|||.|||....|.|||.:.:.:.::
Human     9 VLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVL 73

  Fly    65 TAGHCLHERSVTL-MKVRVGAQNHNYGGT-----LVPVAAYKVHEQFDSRFLHYDIAVLRLSTPL 123
            ||.||...|::.. .:||:||.  ..|.|     .|||....:...:.......|:|:|:|..|:
Human    74 TAAHCFPRRALPAEYRVRLGAL--RLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPV 136

  Fly   124 TFGLSTR----AINLASTSPSGGTTVTVTGWGHTDNGA-LSD--SLQKAQLQIIDRGECASQKFG 181
            .  ||.|    .:.:....|..||...|||||....|. |.:  .||..::.::|...| ...:.
Human   137 P--LSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTC-DGLYH 198

  Fly   182 YGADFVGEE------TICAASTDA--DACTGDSGGPLV----ASSQLVGIVSWGYRCADDNYPGV 234
            .|||....|      ::||.....  |||.|||||||.    .|..|||:||||..||..|.|||
Human   199 VGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGV 263

  Fly   235 YADVAILRPWI 245
            |..||...|||
Human   264 YTSVATYSPWI 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	85/242 (35%)
PRSS33	NP_690851.2	Tryp_SPc	37..275	CDD:238113	86/243 (35%)