Protein Alignment iotaTry and CTRB1

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001897.4
• Gene: CTRB1 / 1504
• HGNCID: 2521
• Length: 263
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 85/237 - (35%)
• Similarity: 120/237 - (50%)
• Gaps: 19/237 - (8%)

  Fly    27 RIIGGSDQLIRNAPWQVSIQ-ISARHECGGVIYSKEIIITAGHCLHERS--VTLMKVRVGAQNHN 88
            ||:.|.|.:..:.|||||:| .:..|.|||.:.|::.::||.||....|  |...:...|:...|
Human    33 RIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEEN 97

  Fly    89 YGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGLSTRAINLASTSPS--GGTTVTVTGWG 151
            .  .::.:|....:.:|....::.||.:|:|:||..|..:..|:.|.|....  .||....||||
Human    98 I--QVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWG 160

  Fly   152 HTDNGA--LSDSLQKAQLQIIDRGECASQKFGYGADFVGEETICAASTDADACTGDSGGPLVASS 214
            .|...|  ..|.||:|.|.::...||   |..:|.. :.:..|||.::...:|.||||||||...
Human   161 KTKYNANKTPDKLQQAALPLLSNAEC---KKSWGRR-ITDVMICAGASGVSSCMGDSGGPLVCQK 221

  Fly   215 Q----LVGIVSWGYRCADDNYPGVYADVAILRPWIVK--AAN 250
            .    ||||||||......:.|||||.|..|.||:.|  |||
Human   222 DGAWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKILAAN 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	80/228 (35%)
CTRB1	NP_001897.4	Tryp_SPc	34..259	CDD:238113	80/230 (35%)