DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and tmprss4a

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_005157547.1	Gene:	tmprss4a / 777630	ZFINID:	ZDB-GENE-061103-631	Length:	458	Species:	Danio rerio

Alignment Length:	283	Identity:	104/283 - (36%)
Similarity:	137/283 - (48%)	Gaps:	55/283 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CALGGTVPE--------------------------GLLPQLDGRIVGGSATTISSFPWQISLQRS 51
            |.:|.|.|:                          ||....| |||||....|:::|||:|||.|
Zfish   181 CMVGTTKPQTFQSAVSDRKVCSTGTVISLSCSADCGLSRNQD-RIVGGKDADIANWPWQVSLQYS 244

  Fly    52 GSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWS-SGGVTFSVSSFKNHEGYNANTMVN 115
            |.|:||||:.:.|.:||||||........|      |.|: ..|:|:..|:   ...|....:||
Zfish   245 GQHTCGGSLVTPNWVVTAAHCFNGDGRKAL------SRWTVVSGITYLSST---PSSYVKEIIVN 300

  Fly   116 ----------DIAIIKINGALTFSSTIKAIGLASSNPA--NGAAASVSGWGTLSYGSSSIPSQLQ 168
                      ||.:||:...:|.|.:.:.:.|...|..  .|....|:|||.::....|:.|.||
Zfish   301 SNYKPAESDFDITMIKLQSPITLSESRRPVCLPPQNLGLKGGDGLVVTGWGHMAEKGGSLSSMLQ 365

  Fly   169 YVNVNIVSQSQCASSTYGYGSQIRSTMICAA--ASGKDACQGDSGGPLV---SGGVLVGVVSWGY 228
            ...:.::..:||:|.|. |||.|...||||.  |.|.||||||||||||   ...|||||||||.
Zfish   366 KAQIQVIDSAQCSSPTV-YGSSITPRMICAGVMAGGVDACQGDSGGPLVHLADRWVLVGVVSWGV 429

  Fly   229 GCAYSNYPGVYADVAALRSWVIS 251
            |||...:||||.:|..:..|..|
Zfish   430 GCARPGFPGVYTNVDQMLDWAHS 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	95/236 (40%)
tmprss4a	XP_005157547.1	LDLa	74..105	CDD:238060
		SRCR_2	121..218	CDD:295335	5/36 (14%)
		Tryp_SPc	223..449	CDD:214473	95/235 (40%)
		Tryp_SPc	224..449	CDD:238113	94/234 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910