DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and TPSAB1

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_003285.2	Gene:	TPSAB1 / 7177	HGNCID:	12019	Length:	275	Species:	Homo sapiens

Alignment Length:	271	Identity:	89/271 - (32%)
Similarity:	128/271 - (47%)	Gaps:	26/271 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLKFVILLSAVACALGGTVP-EGLLPQLDGRIVGGSATTISSFPWQISLQRSG---SHSCGGSIY 61
            ||..::|...|..:.....| .|...|..| ||||.....|.:|||:||:..|   .|.||||:.
Human     1 MLNLLLLALPVLASRAYAAPAPGQALQRVG-IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLI 64

  Fly    62 SSNVIVTAAHC----LQSVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKI 122
            ....::|||||    ::.::|..:|:|....|:..  ....||....|..:....:..|||::::
Human    65 HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD--QLLPVSRIIVHPQFYTAQIGADIALLEL 127

  Fly   123 NGALTFSSTIKAIGL--ASSNPANGAAASVSGWGTLSYGSS-SIPSQLQYVNVNIVSQSQCASST 184
            ...:..||.:..:.|  ||.....|....|:|||.:..... ..|..|:.|.|.|:....| .:.
Human   128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC-DAK 191

  Fly   185 YGYGSQ-------IRSTMICAAASGKDACQGDSGGPL---VSGGVL-VGVVSWGYGCAYSNYPGV 238
            |..|:.       :|..|:||..:.:|:|||||||||   |:|..| .||||||.|||..|.||:
Human   192 YHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGI 256

  Fly   239 YADVAALRSWV 249
            |..|.....|:
Human   257 YTRVTYYLDWI 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	80/239 (33%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	81/240 (34%)
TPSAB1	NP_003285.2	Tryp_SPc	31..267	CDD:214473	80/238 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4288
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960