DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and Tmprss11a

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_038948511.1	Gene:	Tmprss11a / 686581	RGDID:	1596322	Length:	387	Species:	Rattus norvegicus

Alignment Length:	246	Identity:	87/246 - (35%)
Similarity:	128/246 - (52%)	Gaps:	29/246 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSS 88
            :|.:..|||.|:.....::|||:||||:..|.|||::..:..:||||||.::        .|...
  Rat   149 IPLIANRIVSGNPAAKGAWPWQVSLQRNNIHQCGGTLIGNMWVVTAAHCFRT--------NANPR 205

  Fly    89 YWS-SGGVTFSVSSFKN-------HEGYNANTMVNDIAIIKINGALTFSSTIKAIGL---ASSNP 142
            .|: |.|.|.:....|.       ||.|......:|||:::.:..:|||..::.|.|   ::|.|
  Rat   206 QWTLSFGTTINPPLMKREVRRIIMHEKYRPPARDHDIALVQFSPRVTFSDEVRRICLPEPSASFP 270

  Fly   143 ANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA-ASG-KDA 205
            .| :...::|:|.|.||..| .::|:...|.|:|...| ...:.||::|:..|.||. ..| .||
  Rat   271 PN-STVYITGFGALYYGGES-QNELREARVQIISNDVC-KQRHVYGNEIKRGMFCAGFLEGIYDA 332

  Fly   206 CQGDSGGPLV-----SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWVIS 251
            |:||||||||     ....|:|:||||..|...|.||||..|...|.|:.|
  Rat   333 CRGDSGGPLVVRDDKDTWYLIGIVSWGDNCGQKNKPGVYTQVTYYRRWIAS 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	84/236 (36%)
Tmprss11a	XP_038948511.1	SEA	35..133	CDD:396113
Tmprss11a	XP_038948511.1	Tryp_SPc	156..384	CDD:238113	85/239 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910