DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gammaTry and ST14

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	244	Identity:	82/244 - (33%)
Similarity:	119/244 - (48%)	Gaps:	26/244 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSG-SHSCGGSIYSSNVIVTAAHCL----------QSVSASVLQI 83
            |:|||:......:|||:||...| .|.||.|:.|.|.:|:||||.          .:...:.|.:
Human   614 RVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGL 678

  Fly    84 RAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTIKAIGLASSN---PANG 145
            ...|...:.|.....:....:|..:|..|...|||::::.....:||.::.|.|..::   || |
Human   679 HDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFPA-G 742

  Fly   146 AAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA--ASGKDACQG 208
            .|..|:|||...||.:. ...||...:.:::|:.|.:.   ...||...|:|..  :.|.|:|||
Human   743 KAIWVTGWGHTQYGGTG-ALILQKGEIRVINQTTCENL---LPQQITPRMMCVGFLSGGVDSCQG 803

  Fly   209 DSGGPLVS----GGVL-VGVVSWGYGCAYSNYPGVYADVAALRSWVISN 252
            ||||||.|    |.:. .||||||.|||..|.||||..:...|.|:..|
Human   804 DSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKEN 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	80/239 (33%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SEA	88..>171	CDD:307516
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	80/241 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910