DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and f2

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001015797.1	Gene:	f2 / 548514	XenbaseID:	XB-GENE-481539	Length:	607	Species:	Xenopus tropicalis

Alignment Length:	257	Identity:	78/257 - (30%)
Similarity:	122/257 - (47%)	Gaps:	36/257 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LDGRIVGGSATTISSFPWQISLQRSGSHS--CGGSIYSSNVIVTAAHCL------QSVSASVLQI 83
            :.||||.|......|.|||:.|.:.....  ||.|:.|...:::||||:      ::.:...:.:
Frog   346 MQGRIVKGETAEPGSAPWQVMLFKKSPQELLCGASLLSDRWVLSAAHCIFYPPWDKNYTTDDILV 410

  Fly    84 RAGSSYWSS-GGVTFSVSSFKN---HEGYN-ANTMVNDIAIIKINGALTFSSTIKAIGLASSNP- 142
            |.|..:.:. ...|..::..:.   |..|| ...:..|||:|::...:.||:.|..:.|.:.:.
Frog   411 RIGKHFRTKYERATERIAQLERIIVHPKYNWKENLDRDIALIQLKRPVAFSNYIHPVCLPTKDTV 475

  Fly   143 ----ANGAAASVSGWGTL----SYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA 199
                |.|....|:|||.|    :.|:.::|..||.:|:.||.|..|.|||   ..::...|.||.
Frog   476 VKLLAAGYKGRVTGWGNLQETWTSGAQNLPQALQQINLPIVDQETCKSST---NIKVTDNMFCAG 537

  Fly   200 ASGK-----DACQGDSGGPLV------SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWVI 250
            .:.:     |||:||||||.|      ...|.:|:||||.||...|..|.|..|..:|.|::
Frog   538 YNPEDSKRGDACEGDSGGPFVMKDPDTGRWVQLGIVSWGEGCDRDNKYGFYVHVHRMRKWIM 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	76/251 (30%)
f2	NP_001015797.1	GLA	23..86	CDD:214503
		KR	106..185	CDD:214527
		KR	206..287	CDD:214527
		Thrombin_light	303..349	CDD:370463	0/2 (0%)
		Tryp_SPc	349..598	CDD:214473	76/251 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910