DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gammaTry and Tmprss2

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_056590.2	Gene:	Tmprss2 / 50528	MGIID:	1354381	Length:	490	Species:	Mus musculus

Alignment Length:	268	Identity:	89/268 - (33%)
Similarity:	126/268 - (47%)	Gaps:	39/268 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIV 67
            :.|:.|..:.|.:...       :...|||||...:...:|||:||...|.|.|||||.:...||
Mouse   233 RMVVSLRCIECGVRSV-------KRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIV 290

  Fly    68 TAAHCLQSVSASVLQIRAGSSYWSS-----------GGVTFSVSSFKNHEGYNANTMVNDIAIIK 121
            |||||::...:|       ..||::           .|....|....:|..|::.|..||||::|
Mouse   291 TAAHCVEEPLSS-------PRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMK 348

  Fly   122 INGALTFSSTIKAIGLASSNPAN----GAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCAS 182
            :...|.|:..:|.:.|  .||..    .....:||||. :|........|....|.::..|:| :
Mouse   349 LQTPLAFNDLVKPVCL--PNPGMMLDLDQECWISGWGA-TYEKGKTSDVLNAAMVPLIEPSKC-N 409

  Fly   183 STYGYGSQIRSTMICAA--ASGKDACQGDSGGPLVS--GGV--LVGVVSWGYGCAYSNYPGVYAD 241
            |.|.|.:.|...||||.  ....|:||||||||||:  .|:  |:|..|||.|||.:..||||.:
Mouse   410 SKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGN 474

  Fly   242 VAALRSWV 249
            |.....|:
Mouse   475 VTVFTDWI 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	85/239 (36%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:373897	3/13 (23%)
		Tryp_SPc	254..485	CDD:238113	85/240 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910