DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and Corin

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	75/250 - (30%)
Similarity:	116/250 - (46%)	Gaps:	39/250 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHS---CGGSIYSSNVIVTAAHCLQSVSASVLQ---IRAGSS 88
            ||:||:..:..::|:..:: ..|...   |.|.:.|...::||:||:.:.|...|:   |:.|.:
  Fly  1103 RIIGGTQASPGNWPFLAAI-LGGPEKIFYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVT 1166

  Fly    89 YWSS---GGVTFSVSSFKNHEGYN-ANTMVNDIAIIKINGALTFSSTIKAIGLASSNPAN---GA 146
            ..:|   .|....|.:...|..|| |....||||:.::...:.|...:..:.|...:..|   |.
  Fly  1167 RRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGT 1231

  Fly   147 AASVSGWGTLSYGSSSIPSQLQY----VNVNIVSQSQC----ASSTYGYGSQIRSTMICAA--AS 201
            ..:|.|||...  .....|..:|    |.|.|::::||    .:.|...|      |:||.  ..
  Fly  1232 LCTVIGWGKRE--DKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTVSEG------MVCAGFDDG 1288

  Fly   202 GKDACQGDSGGPLV-------SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            |||||||||||||:       :...:.|:||||..||:...|||||:|.....|:
  Fly  1289 GKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWI 1343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	74/248 (30%)
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931
		Tryp_SPc	1103..1343	CDD:214473	74/248 (30%)
		Tryp_SPc	1104..1346	CDD:238113	74/248 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910