DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and TMPRSS7

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001382436.1	Gene:	TMPRSS7 / 344805	HGNCID:	30846	Length:	843	Species:	Homo sapiens

Alignment Length:	244	Identity:	85/244 - (34%)
Similarity:	120/244 - (49%)	Gaps:	37/244 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWSS-- 92
            ||:||:.|....:|||:||...||..||.|:.|...:::||||......|      ..:.|::
Human   605 RIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLS------DPTPWTAHL 663

  Fly    93 -----GGVTFSVSSFKN---HEGYNANTMVNDIAIIKINGALTFSSTIK------AIGLASSNPA 143
                 |...| ||..:.   ||.||:.|...|||::::  ::.:..|:|      .|........
Human   664 GMYVQGNAKF-VSPVRRIVVHEYYNSQTFDYDIALLQL--SIAWPETLKQLIQPICIPPTGQRVR 725

  Fly   144 NGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA-ASGK-DAC 206
            :|....|:|||......:.....||...|.::.|:.|. ||||.   |.|.|:||. .||| |||
Human   726 SGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCV-STYGI---ITSRMLCAGIMSGKRDAC 786

  Fly   207 QGDSGGPL----VSGG--VLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            :|||||||    .|.|  :|.|:||||:|....|:||||..|:....|:
Human   787 KGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWI 835

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	84/242 (35%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..67
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910