DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and OVCH2

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_016873148.1	Gene:	OVCH2 / 341277	HGNCID:	29970	Length:	569	Species:	Homo sapiens

Alignment Length:	246	Identity:	81/246 - (32%)
Similarity:	121/246 - (49%)	Gaps:	28/246 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSVS-ASVLQIRAGS---SYW 90
            ||:|||.....|:|||:||::...|.|||||.|...::|||||:.:.: .|.|.:.||.   |..
Human    55 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQT 119

  Fly    91 SSGGVTFSVSSFKNHEGYNA-NTMVNDIAIIKINGALTFSSTIKAIGLASSNP--ANGAAASVSG 152
            ..|..|.::.:...|..::. ..|..|||::|:.||..|...:..|.|.....  ..|...:.:|
Human   120 DPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAG 184

  Fly   153 WGTLSYGSSSIPSQ-LQYVNVNIVSQSQCASSTYGYGSQIR-STMICAA--ASGKDACQGDSGGP 213
            ||.|:.|  .:.|| ||.||:.|::..:|.::.......|. .|.:|..  ..|:|||||||||.
Human   185 WGRLTEG--GVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGS 247

  Fly   214 LV-----SGGVLVGVVSWGYGC----------AYSNYPGVYADVAALRSWV 249
            |:     ....|.||.|||.||          :....||::.|::.:..|:
Human   248 LMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	80/244 (33%)
OVCH2	XP_016873148.1	Tryp_SPc	55..298	CDD:214473	80/244 (33%)
		Tryp_SPc	56..301	CDD:238113	80/245 (33%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910