DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and plg

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_958880.2	Gene:	plg / 322691	ZFINID:	ZDB-GENE-030131-1411	Length:	818	Species:	Danio rerio

Alignment Length:	259	Identity:	85/259 - (32%)
Similarity:	121/259 - (46%)	Gaps:	38/259 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 AVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGS-HSCGGSIYSSNVIVTAAHCL 73
            ::.|....|.|:    :..||||||..:...|:||||||:..|. |.|||::.....:|||||||
Zfish   572 SLKCGQPATKPK----RCFGRIVGGCVSKPHSWPWQISLRTRGKIHFCGGTLIDPQWVVTAAHCL 632

  Fly    74 Q-SVSASVLQI-------RAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSS 130
            : |.|.|..:|       ||..|......||   ...|...|       .|||::|::.....:.
Zfish   633 ERSDSPSAYKIMLGIHTERATESSKQERDVT---KIIKGPAG-------TDIALLKLDRPALIND 687

  Fly   131 TIKAIGLASSN---PANGAAASVSGWG-TLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQI 191
            .:..:.|...:   |:| ....|:||| |...|..   ..|:.....::....|...::..| ::
Zfish   688 KVSPVCLPEKDYIVPSN-TECYVTGWGETQDTGGE---GYLKETGFPVIENKVCNRPSFLNG-RV 747

  Fly   192 RSTMICAA--ASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            :...:||.  ..|.|:||||||||||    :..||.||.|||.|||.:..||||..|:....|:
Zfish   748 KDHEMCAGNIEGGNDSCQGDSGGPLVCYAQNTFVLQGVTSWGLGCANAMKPGVYTRVSKFVDWI 811

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	80/237 (34%)
plg	NP_958880.2	PAN_AP_HGF	31..104	CDD:238532
		KR	109..190	CDD:214527
		KR	190..270	CDD:214527
		KR	281..361	CDD:214527
		Kringle	376..453	CDD:306546
		KR	490..572	CDD:214527	85/259 (33%)
		Tryp_SPc	589..813	CDD:238113	80/238 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910