DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and Tmprss3

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	91/256 - (35%)
Similarity:	127/256 - (49%)	Gaps:	21/256 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTA 69
            |:.|...||        |:......|||||:.::::.:|||:|||..|.|.||||:.:...||||
  Rat   199 VVTLKCSAC--------GMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGYHLCGGSVITPLWIVTA 255

  Fly    70 AHCLQSV---SASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSST 131
            |||:..:   .:..:|:.. .|...|...:..|.....|..|....:.||||::|::..|||..|
  Rat   256 AHCVYDLYHPKSWTVQVGL-VSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDET 319

  Fly   132 IKAIGLASS--NPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRST 194
            |:.|.|.:|  |..:|.....||||....|:......|.:..|.::|...|..... ||..|..:
  Rat   320 IQPICLPNSEENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDV-YGGIISPS 383

  Fly   195 MICAA--ASGKDACQGDSGGPLVSG----GVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            |:||.  ..|.|:||||||||||..    ..|||..|:|.|||..|.||||..:.:...|:
  Rat   384 MLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	85/229 (37%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	5/19 (26%)
		Tryp_SPc	216..444	CDD:214473	85/229 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910