Protein Alignment gammaTry and GZMH

DIOPT Version :9

• Sequence 1: NP_725034.1
• Gene: gammaTry / 36221
• FlyBaseID: FBgn0010359
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_219491.1
• Gene: GZMH / 2999
• HGNCID: 4710
• Length: 246
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 74/271 - (27%)
• Similarity: 110/271 - (40%)
• Gaps: 54/271 - (19%)

  Fly     1 MLKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQI---SLQRSGSHSCGGSIYS 62
            |..|::||:.:.....||          ..|:||......|.|:..   .||......|||.:..
Human     1 MQPFLLLLAFLLTPGAGT----------EEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVR 55

  Fly    63 SNVIVTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFKN---------------HEGYNANT 112
            .:.::|||||            .|||.    .||....:.|.               |..||...
Human    56 KDFVLTAAHC------------QGSSI----NVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKN 104

  Fly   113 MVNDIAIIKINGALTFSSTIKAIGLASSNP--ANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIV 175
            ..|||.::::.....:::.::.:.|.||..  ..|...||:|||.:|  .|::.:.||.|.:.:
Human   105 FSNDIMLLQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVS--MSTLATTLQEVLLTV- 166

  Fly   176 SQSQCASSTYGYGSQIRSTMICAAASGK--DACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGV 238
             |..|......:|:..|:|.||.....|  ...:||||||||...|..|::|  ||......|||
Human   167 -QKDCQCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILS--YGNKKGTPPGV 228

  Fly   239 YADVAALRSWV 249
            |..|:....|:
Human   229 YIKVSHFLPWI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	67/240 (28%)
GZMH	NP_219491.1	Tryp_SPc	21..242	CDD:238113	68/241 (28%)
		Mediates the preference for acidic residues at the P3' and P4' sites	46..48		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910