DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and Hpn

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_038958880.1	Gene:	Hpn / 29135	RGDID:	61982	Length:	559	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	91/244 - (37%)
Similarity:	133/244 - (54%)	Gaps:	29/244 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCL--QSVSASVLQIRAGS-SYWS 91
            |||||..:::..:|||:||:..|:|.||||:.|.:.::|||||.  ::...|..::.||: :..|
  Rat   203 RIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTS 267

  Fly    92 SGGVTFSVSSFKNHEGY--------NANTMVNDIAIIKINGALTFSSTIKAIGLASSNPA--NGA 146
            ...|...|.:...|.||        :.|:  ||||::.::.:|..:..|:.:.|.::..|  :|.
  Rat   268 PHAVQLGVQAVIYHGGYLPFRDPTIDENS--NDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGK 330

  Fly   147 AASVSGWG-TLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA--ASGKDACQG 208
            ..:|:||| |..||..::  .||...|.|:|...|.|..: ||:||:..|.||.  ..|.|||||
  Rat   331 VCTVTGWGNTQFYGQQAV--VLQEARVPIISNEVCNSPDF-YGNQIKPKMFCAGYPEGGIDACQG 392

  Fly   209 DSGGPLV--------SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            |||||.|        |...|.|:||||.|||.:..||||..|...|.|:
  Rat   393 DSGGPFVCEDRISGTSRWRLCGIVSWGTGCALARKPGVYTKVIDFREWI 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	90/242 (37%)
Hpn	XP_038958880.1	Hepsin-SRCR	92..200	CDD:401275
Hpn	XP_038958880.1	Tryp_SPc	204..441	CDD:238113	89/241 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910