Protein Alignment gammaTry and KLK5

DIOPT Version :10

• Sequence 1: NP_725034.1
• Gene: gammaTry / 36221
• FlyBaseID: FBgn0010359
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 87/252 - (34%)
• Similarity: 124/252 - (49%)
• Gaps: 27/252 - (10%)

  Fly    18 TVPEGLLPQL-------------DGRIVGGSATTISSFPWQIS-LQRSGSHSCGGSIYSSNVIVT 68
            |||.|....|             ..||:.||...:.:.|||.: |.|.....||..:.....::|
Human    41 TVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLT 105

  Fly    69 AAHCLQSVSASVLQIRAG----SSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFS 129
            ||||.:    .|.::|.|    |..:.||...|.......|.||:.....||:.:||:|..:..:
Human   106 AAHCRK----KVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPT 166

  Fly   130 STIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRST 194
            ..::.|.::|..|:.|....||||||........|..||.:|::::||.:|..:   |..||..|
Human   167 KDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDA---YPRQIDDT 228

  Fly   195 MICAA-ASGKDACQGDSGGPLVSGGVLVGVVSWG-YGCAYSNYPGVYADVAALRSWV 249
            |.||. .:|:|:||||||||:|..|.|.|:|||| |.||..|.||||.::.....|:
Human   229 MFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	81/225 (36%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/26 (23%)
		Tryp_SPc	66..285	CDD:214473	81/225 (36%)