DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gammaTry and Klkb1

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	87/249 - (34%)
Similarity:	118/249 - (47%)	Gaps:	36/249 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QLDGRIVGGSATTISSFPWQISLQ---RSGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGS 87
            :::.|||||:.:::..:|||:|||   .|.:|.|||||.....|:|||||...:..        .
  Rat   386 KINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHCFDGIPY--------P 442

  Fly    88 SYWSSGGVTFSVSSFKN------------HEGYNANTMVNDIAIIKINGALTFSSTIKAIGLASS 140
            ..|...|...::|...|            |:.|..:....|||:||:...|.::...|.|.|.|.
  Rat   443 DVWRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEGSYDIALIKLQTPLNYTEFQKPICLPSK 507

  Fly   141 NPANGAAAS--VSGWG-TLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA--A 200
            ...|....:  |:||| |...|.:.  :.||...:.:|...:|......|  .|...||||.  .
  Rat   508 ADTNTIYTNCWVTGWGYTKERGETQ--NILQKATIPLVPNEECQKKYRDY--VITKQMICAGYKE 568

  Fly   201 SGKDACQGDSGGPLV---SG-GVLVGVVSWGYGCAYSNYPGVYADVAALRSWVI 250
            .|.|||:||||||||   || ..|||:.|||.|||....||||..||....|::
  Rat   569 GGIDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKEQPGVYTKVAEYIDWIL 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	86/242 (36%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519
		Tryp_SPc	390..621	CDD:214473	86/242 (36%)
		Tryp_SPc	391..621	CDD:238113	85/241 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910