DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and Tmprss11f

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_848845.1	Gene:	Tmprss11f / 243083	MGIID:	2442348	Length:	439	Species:	Mus musculus

Alignment Length:	249	Identity:	81/249 - (32%)
Similarity:	116/249 - (46%)	Gaps:	46/249 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTI-SSFPWQISLQRSGS-HSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWSS 92
            |||.|..|.: ..:|||.|||..|: |.||.::.|:..::|||||                :|.:
Mouse   206 RIVQGRETAMEGEWPWQASLQLIGAGHQCGATLISNTWLLTAAHC----------------FWKN 254

  Fly    93 GG-----VTF-----------SVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTIKAIGLASSN 141
            ..     |||           ||.....||.|:.:|..||||:.::...:.||:.::.:.|..|:
Mouse   255 RDPTKWIVTFGTTITPPLVKRSVGKIIIHEEYHRDTNENDIALAQLTTRVEFSNVVQRVCLPDSS 319

  Fly   142 ---PANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA-ASG 202
               |.. .:..|:|:|:: .......::|:...|..:....|..... |...|...|:||. ..|
Mouse   320 MKLPPK-TSVFVTGFGSI-VDDGPTQNKLRQARVETIGSDVCNRKDV-YDGLITPGMLCAGFMEG 381

  Fly   203 K-DACQGDSGGPLVSGG----VLVGVVSWGYGCAYSNYPGVYADVAALRSWVIS 251
            | |||:||||||||...    .:||:||||..||..|.||||..|...|.|:.|
Mouse   382 KIDACKGDSGGPLVYDNRDIWYIVGIVSWGQSCALPNKPGVYTRVTKYRDWIAS 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	79/245 (32%)
Tmprss11f	NP_848845.1	SEA	60..164	CDD:396113
Tmprss11f	NP_848845.1	Tryp_SPc	207..436	CDD:238113	80/248 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910