DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	253	Identity:	92/253 - (36%)
Similarity:	140/253 - (55%)	Gaps:	34/253 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSVSASVL 81
            |..|: |:...:.||:||.......:|||:|||.:..|.|||::.|:..::|||||.:|.
Mouse   173 GARPD-LITLSEERIIGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCFKSY----- 231

  Fly    82 QIRAGSSYWSSGGVTFSVSSFK-----------NHEGYNANTMVNDIAIIKINGALTFSSTIKAI 135
               ....||::   ||.||:..           .|:||::.|..||||:::::.::.||..|..:
Mouse   232 ---PNPQYWTA---TFGVSTMSPRLRVRVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRV 290

  Fly   136 GL--ASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICA 198
            .|  |:.|...|:.|.|:|||:|:||.::: :.|:...|.|:|..:| ::..||...:...|:||
Mouse   291 CLPAATQNIIPGSVAYVTGWGSLTYGGNAV-TNLRQGEVRIISSEEC-NTPAGYSGSVLPGMLCA 353

  Fly   199 A--ASGKDACQGDSGGPLVSGG-----VLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            .  :...||||||||||||...     .:||:|||||.|...|.||||..|.|.|:|:
Mouse   354 GMRSGAVDACQGDSGGPLVQEDSRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	88/238 (37%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	88/238 (37%)
		Tryp_SPc	186..414	CDD:238113	88/239 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910