DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and Tmprss4

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_663378.1	Gene:	Tmprss4 / 214523	MGIID:	2384877	Length:	435	Species:	Mus musculus

Alignment Length:	230	Identity:	80/230 - (34%)
Similarity:	122/230 - (53%)	Gaps:	14/230 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQS-VSASVLQIRAGSSYWSSG 93
            |:|||....:.|:|||:|:|.:..|.|||||...:.|:|||||.:. :..|..::||||:...:
Mouse   202 RVVGGVEAPVDSWPWQVSIQYNKQHVCGGSILDPHWILTAAHCFRKYLDVSSWKVRAGSNILGN- 265

  Fly    94 GVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTIKAIGLASSN----PANGAAASVSGWG 154
            ..:..|:.....|.........|||::|:...||||.:::.|.|..|:    ||  ....|.|||
Mouse   266 SPSLPVAKIFIAEPNPLYPKEKDIALVKLQMPLTFSGSVRPICLPFSDEVLVPA--TPVWVIGWG 328

  Fly   155 TLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAAA--SGKDACQGDSGGPLV-- 215
            ........:...|...:|.::..::| ::...|..::.:.|:||..  .|||.|||||||||:
Mouse   329 FTEENGGKMSDMLLQASVQVIDSTRC-NAEDAYEGEVTAEMLCAGTPQGGKDTCQGDSGGPLMYH 392

  Fly   216 -SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
             ....:||:||||:||...:.||||..|.|..:|:
Mouse   393 SDKWQVVGIVSWGHGCGGPSTPGVYTKVTAYLNWI 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	79/228 (35%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:295335
		Tryp_SPc	202..427	CDD:214473	79/228 (35%)
		Tryp_SPc	203..430	CDD:238113	79/229 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910