DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and PRSS58

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001001317.1	Gene:	PRSS58 / 136541	HGNCID:	39125	Length:	241	Species:	Homo sapiens

Alignment Length:	267	Identity:	65/267 - (24%)
Similarity:	104/267 - (38%)	Gaps:	52/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVI 66
            :||::|.:    .|..||.....|..          |:||.|..:...:|....|.|.:.....:
Human     1 MKFILLWA----LLNLTVALAFNPDY----------TVSSTPPYLVYLKSDYLPCAGVLIHPLWV 51

  Fly    67 VTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFK------------NHEGYNANTMVNDIAI 119
            :|||||.......:|            |||....|.:            :|..::..::.:||.:
Human    52 ITAAHCNLPKLRVIL------------GVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDHDIML 104

  Fly   120 IKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSI---PSQLQYVNVNIVSQSQC- 180
            ||:......:..:|...|.....:.....|||.|   ||....|   |..||.||::::|:.||
Human   105 IKLKTEAELNDYVKLANLPYQTISENTMCSVSTW---SYNVCDIYKEPDSLQTVNISVISKPQCR 166

  Fly   181 -ASSTYGYGSQIRSTMICA--AASGKDACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYADV 242
             |..||    .|...|:|.  ....:..|:..|..|.:..|:|.|::|:..||......|:||.:
Human   167 DAYKTY----NITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKI 227

  Fly   243 AALRSWV 249
            .....|:
Human   228 FYYIPWI 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	57/237 (24%)
PRSS58	NP_001001317.1	Tryp_SPc	29..234	CDD:214473	53/223 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910