DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and AgaP_AGAP001365

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_321778.5	Gene:	AgaP_AGAP001365 / 1281817	VectorBaseID:	AGAP001365	Length:	608	Species:	Anopheles gambiae

Alignment Length:	270	Identity:	70/270 - (25%)
Similarity:	112/270 - (41%)	Gaps:	48/270 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCL---- 73
            ||   ||.|.:..::..||:||..:.....||.:::.....:.|||||.....|:||||||
Mosquito   349 CA---TVLEPVGTRIRSRIIGGVTSNQGEHPWHVAIYLDEEYQCGGSIIGRRWILTAAHCLTRQN 410

  Fly    74 --QSVSASVLQIRAGSSYWSSGGVTFSVSSFKN-----------HEGYNANTMVNDIAIIKINGA 125
              :::...:.::..|         ...:|:..:           |..||......||.::::...
Mosquito   411 TNETLDVDLFRVYTG---------IIDISTIDDHFYRTADEVIVHRDYNPVMYTTDIGLLRLKRN 466

  Fly   126 LTFSSTIKAIGL----ASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYG 186
            :|::|.||.:.|    ...:...|....|:|||....|  .|.:.|.|:.|.:|||..|:.....
Mosquito   467 ITYNSFIKPVCLYNRTVDISTFYGREGKVTGWGFNRDG--VISNVLNYLEVPVVSQKMCSQRNVQ 529

  Fly   187 YGSQIR-STMICAA-ASGKDACQGDSGGPLVSGG----VLVGVVSWGYG------CAYSNYPGVY 239
            :...:. ....||. |.|...|.|||||.||...    .:.|:||....      |..:.| .|:
Mosquito   530 FNGVLAVGESFCAGHADGNSVCNGDSGGGLVFAEGPRYYVRGIVSISAQRRNLLLCDPNQY-SVF 593

  Fly   240 ADVAALRSWV 249
            .||:...:|:
Mosquito   594 TDVSKFLNWI 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	64/251 (25%)
AgaP_AGAP001365	XP_321778.5	GD_N	42..144	CDD:292649
		GD_N	190..297	CDD:292649
		Tryp_SPc	363..603	CDD:214473	64/251 (25%)
		Tryp_SPc	364..606	CDD:238113	64/252 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910