DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and SCRASP1

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_315638.3	Gene:	SCRASP1 / 1276311	VectorBaseID:	AGAP005625	Length:	1322	Species:	Anopheles gambiae

Alignment Length:	242	Identity:	81/242 - (33%)
Similarity:	116/242 - (47%)	Gaps:	22/242 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAG--- 86
            |....|:|.||.|.....|||.||:....|.||..:.:...::||||||.....|..::|.|
Mosquito  1073 PTYGARVVHGSETVYGHHPWQASLRVKTMHWCGAVLITRYHVLTAAHCLIGYPKSTYRVRIGDYH 1137

  Fly    87 SSYWSSGGVTFSVSSFKNHEGY-NANTMVNDIAIIKINGALTFSSTIKAIGLASSNPAN------ 144
            ::.:.:..:...:.:...||.: ..:.|.||||::.:...:.|:..::.|.|    ||.
Mosquito  1138 TAAYDNAELDIFIENTYIHEQFREGHHMSNDIAVVVLKTPVRFNDYVQPICL----PARDAPYLP 1198

  Fly   145 GAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAAA--SGKDACQ 207
            |...::||||....||......|:...|.::..|.|..... ||..:...|.||..  .|.|:|.
Mosquito  1199 GQNCTISGWGATEAGSKDSSYDLRAGTVPLLPDSVCRRPEV-YGDSLIDGMFCAGTLEPGVDSCD 1262

  Fly   208 GDSGGPLV---SGGV--LVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            ||||||||   |.|:  |.|:||||..|.|:|.||||..||..|.|:
Mosquito  1263 GDSGGPLVCPNSEGLHTLTGIVSWGKHCGYANKPGVYLKVAHYRDWI 1309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	79/235 (34%)
SCRASP1	XP_315638.3	ChtBD2	181..228	CDD:214696
		ChtBD2	289..334	CDD:214696
		LDLa	731..762	CDD:238060
		SRCR	776..878	CDD:278931
		SR	776..877	CDD:214555
		LDLa	884..921	CDD:238060
		SR	927..1025	CDD:214555
		SRCR	932..1025	CDD:278931
		Tryp_SPc	1078..1309	CDD:214473	79/235 (34%)
		Tryp_SPc	1079..1312	CDD:238113	79/236 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910