DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and AgaP_AGAP004149

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_313033.3	Gene:	AgaP_AGAP004149 / 1273976	VectorBaseID:	AGAP004149	Length:	543	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	83/285 - (29%)
Similarity:	134/285 - (47%)	Gaps:	51/285 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISL----QRSG--SHSCGGSIYSSNV 65
            :::|..|.|          .::.||:||.......|||...|    |.||  ::.|.||:.::..
Mosquito   268 MINAPLCGL----------SVNTRIIGGETEVPGQFPWMARLAYRNQTSGRVTYRCAGSLITNRH 322

  Fly    66 IVTAAHCLQSV--SASVLQIRAGSSYWSSGGVT----------FSVSSFKNHEGYNANTMVNDIA 118
            ::|.|||:.::  ...::.||.|.  .....||          |::.....||.|:.....||||
Mosquito   323 VITVAHCVTNLIDELQLVSIRLGD--LECNAVTDPRCSARYQDFAIEQIIPHESYDVPKYANDIA 385

  Fly   119 IIKINGALTFSSTIKAIGLASSNPA------NGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQ 177
            :||:.......:.|..:.|.:...|      .|....::|||:.|..|::....||::.:.||..
Mosquito   386 LIKLRETTETYNIISPLCLPTDQYAPYALNLTGQLGIIAGWGSTSNRSNTPSPTLQWLRLPIVDT 450

  Fly   178 SQCASSTYGYGSQIRSTMI------CA-AASGKDACQGDSGGPLVSGG-------VLVGVVSWG- 227
            :.||::...|....|:.:|      || ....:|||||||||||::..       ||:|:||:|
Mosquito   451 AGCANAYARYSVNSRNPIIVSGNQMCAQGQENRDACQGDSGGPLMNEAISTRDRFVLLGLVSFGP 515

  Fly   228 YGCAYSNYPGVYADVAALRSWVISN 252
            ..|..||:||||..::|...|:::|
Mosquito   516 RTCGVSNFPGVYTRISAYIDWILAN 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	78/257 (30%)
AgaP_AGAP004149	XP_313033.3	CLIP	47..92	CDD:288855
		Tryp_SPc	281..537	CDD:214473	78/257 (30%)
		Tryp_SPc	282..537	CDD:238113	77/256 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910