DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and AgaP_AGAP011325

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_309327.4	Gene:	AgaP_AGAP011325 / 1270612	VectorBaseID:	AGAP011325	Length:	631	Species:	Anopheles gambiae

Alignment Length:	270	Identity:	72/270 - (26%)
Similarity:	107/270 - (39%)	Gaps:	62/270 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PQLDGRIVGGSATTISSFPWQISLQRSG-SHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSS 88
            |.::.:|..|....:..:||...||.:. :..|||::.:...::|||||.:. ..|.:.:|.|..
Mosquito   379 PYIEEKIANGIDAILFQYPWMALLQDTELAFVCGGTLINKRYVLTAAHCFRE-KLSKISVRLGEF 442

  Fly    89 YWSSG-------------GVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTIKAIGLASS 140
            ...|.             ....:|.....|:.|:|...|||||:|::....:::..:..|.|..|
Mosquito   443 DLKSDIDCDKRGERCALPPQDIAVERTIKHKDYSARHKVNDIALIRLASEASYNENVMPICLPVS 507

  Fly   141 NPANGAAAS---VSGWGTLSYGSSS----------IPSQL---------QYVNVNIVSQSQCASS 183
             |.......   |||||.....:||          :|:.:         :||.||  |...||
Mosquito   508 -PEMRTVKEIYYVSGWGLTENDTSSDVLQVGLLRQLPNDVCQQLLQRKDKYVTVN--SDQMCA-- 567

  Fly   184 TYGYGSQIRSTMICAAASGKDACQGDSGGPLVSGG-----VLVGVVSWGY-GCAYSNYPGVYADV 242
                          ..|:..|.|.|||||||.:..     |..||||:|. .|.....||||..|
Mosquito   568 --------------IGANRTDNCSGDSGGPLKTVAVNARFVQYGVVSYGLRTCGKETAPGVYTRV 618

  Fly   243 AALRSWVISN 252
            .....|::.|
Mosquito   619 ENYIDWILDN 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	69/260 (27%)
AgaP_AGAP011325	XP_309327.4	Tryp_SPc	44..287	CDD:238113
		Tryp_SPc	46..286	CDD:214473
		Tryp_SPc	384..625	CDD:214473	69/260 (27%)
		Tryp_SPc	385..625	CDD:238113	69/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910