DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and f7

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	264	Identity:	81/264 - (30%)
Similarity:	116/264 - (43%)	Gaps:	32/264 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CALGGTVPEGLLP----------QLD--GRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNV 65
            |......|.|.:|          |:|  .||||||.......|||:.|:......|||.||....
Zfish   166 CRSHEVFPCGKVPLLQAGKAADHQVDLRSRIVGGSECPKGHCPWQVLLKYGEKGFCGGVIYKPTW 230

  Fly    66 IVTAAHCLQSVSASVLQIRAGSSYWSSGGVT---FSVSSFKNHEGYNANTMVNDIAIIKINGALT 127
            |:||||||:.:....|:|.||.........|   ..|.....|..|.:.|..:|||::::...:.
Zfish   231 ILTAAHCLEKLKVKFLRIVAGEHDLEVDEGTEQLIQVDQMFTHPAYVSETADSDIALLRLRTPIV 295

  Fly   128 FSSTIKAIGLASSNPANG-----AAASVSGWGTLSY-GSSSIPSQLQYVNVNIVSQSQCASSTYG 186
            :|.....:.|.....|..     :..:|||||..|. |.:|  ..|:.:.|..:...:|...:
Zfish   296 YSVYAVPVCLPLREMAERELWAVSKHTVSGWGKRSEDGPTS--RLLRRLLVPRIRTQECVQVS-- 356

  Fly   187 YGSQIRSTMICAA--ASGKDACQGDSGGPLVS----GGVLVGVVSWGYGCAYSNYPGVYADVAAL 245
             ...:.|.|.||.  ...:|:|:||||||||:    ...|:|:||||.|||.....|:|..|:..
Zfish   357 -NLTLTSNMFCAGYIEGRQDSCKGDSGGPLVTRYRDTAFLLGIVSWGKGCARPGSYGIYTRVSNY 420

  Fly   246 RSWV 249
            ..|:
Zfish   421 LQWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	74/233 (32%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011
		FXa_inhibition	131..166	CDD:291342	81/264 (31%)
		Tryp_SPc	195..424	CDD:214473	74/233 (32%)
		Tryp_SPc	196..427	CDD:238113	74/234 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910