DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and tmprss2.1

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_004912265.1	Gene:	tmprss2.1 / 101731874	XenbaseID:	XB-GENE-22065907	Length:	482	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	98/256 - (38%)
Similarity:	141/256 - (55%)	Gaps:	21/256 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTA 69
            |:.|..:.|  |.:.     ..:..||||||..::..:|||:|||.:..|.|||||.:.|.|:||
Frog   229 VVTLRCIEC--GSST-----KNVGNRIVGGSQASLGDWPWQVSLQFNERHICGGSIITPNYILTA 286

  Fly    70 AHCLQSVSASVL--QIRAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTI 132
            |||::.|.:|..  .:..||.|.|:||..:||.|...|:.|:..|..||||::::...:|.:||:
Frog   287 AHCVEGVYSSPYPWTVYVGSLYKSTGGTRYSVKSLIGHQNYDTKTKNNDIALMRLKSPITLTSTV 351

  Fly   133 KAIGLASSNP--ANGAAASVSGWG-TLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRST 194
            :.:.|.::..  .:|.:...|||| |:..|:||  ..|....|.::....|..:.. |...:.:|
Frog   352 QPVCLPNAGMLWTSGQSCWTSGWGATIEGGTSS--GVLNAAMVPLIDSDTCNRAVV-YNGAVTAT 413

  Fly   195 MICAA--ASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            ||||.  ..|.|:||||||||||    |...|||..|||.|||..|.||||.::..|..|:
Frog   414 MICAGYLRGGIDSCQGDSGGPLVTKTSSLWWLVGDTSWGTGCANMNKPGVYGNITELLPWI 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	93/229 (41%)
tmprss2.1	XP_004912265.1	LDLa	112..143	CDD:238060
		SRCR_2	148..241	CDD:373897	4/13 (31%)
		Tryp_SPc	248..474	CDD:238113	92/228 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000