DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and f12

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	94/249 - (37%)
Similarity:	130/249 - (52%)	Gaps:	27/249 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCL-QSVSASVLQIRAGSS 88
            |.:..|||||.....:|.|: |:.....:|.||||:.|...|||||||| |..:.:.:.:..|.|
Frog   353 PSIMPRIVGGLVALPASHPY-IAALYIDNHFCGGSLISPCWIVTAAHCLDQRPNVTKISVVLGQS 416

  Fly    89 YWSSGG---VTFSVSSFKNHEGYNANTMVNDIAIIK---ING--ALTFSSTIKAIGLASSNPANG 145
            .:::..   ||..|..:..||.|..:|:.:|||::|   |||  |..||..::.|.|    |...
Frog   417 RFNTTDQHTVTLLVEKYILHEKYYGDTLQHDIALVKVKSINGLCASEFSQFVQPICL----PQQF 477

  Fly   146 AAAS------VSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA--ASG 202
            ..|.      |:|||....|:......||..::.|:..:||.|.:. :|.::...|:||.  ..|
Frog   478 KMAESTKQCVVAGWGHQYEGAEHYAFFLQEASMPIIPYTQCQSPSV-HGDRMLPGMLCAGFMEGG 541

  Fly   203 KDACQGDSGGPL---VSGGV-LVGVVSWGYGCAYSNYPGVYADVAALRSWVISN 252
            .|||||||||||   |.|.: |.||||||.|||..|.||||..|.:...|:.:|
Frog   542 VDACQGDSGGPLVCEVDGRIELHGVVSWGSGCAEENKPGVYTAVTSYTDWIRAN 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	91/239 (38%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	91/241 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910