DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and klkb1

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	81/250 - (32%)
Similarity:	122/250 - (48%)	Gaps:	40/250 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQIS--LQRSGS---HSCGGSIYSSNVIVTAAHC--------LQSVSASVL 81
            |||||:.:.:..:|||:|  |:.:.|   |:|||||.|:..|||||||        :..:.:.|:
Frog   390 RIVGGTDSVLGEWPWQVSMHLRLTASYKKHACGGSIISNQWIVTAAHCFAMHPLPQMWIIYSGVV 454

  Fly    82 QIRAGSSYWSSGGVTFSVSSFKN-----HEGYNANTMVNDIAIIKINGALTFSSTIKAIGLASSN 141
            ::         ..:|.|....:.     |..|.......|||::|:...::|:...|||.|....
Frog   455 KL---------SNITQSTPFSETEQIIIHPHYTGAGNGTDIALLKLKTPISFNDHQKAICLPPRE 510

  Fly   142 PANGAAAS--VSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGY-GSQIRSTMICAA-ASG 202
            |......|  ::||| .:..|.|:.:.||...|..:|..:|..:   | .::|...::||. ..|
Frog   511 PTFVLPNSCWITGWG-FTEESGSLANILQKAEVPQISTEECQGN---YEQTRIDKKILCAGYKRG 571

  Fly   203 K-DACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWVISN 252
            | |:|:|||||||.    ....|.|:.|||.|||....||||..|:....|:|.:
Frog   572 KIDSCKGDSGGPLACVVDEIWYLTGITSWGEGCARPGKPGVYTRVSEFTDWIIEH 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	79/245 (32%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519
		Tryp_SPc	391..626	CDD:238113	80/247 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910