DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTry and tmprss3a

DIOPT Version :9

Sequence 1:	NP_725034.1	Gene:	gammaTry / 36221	FlyBaseID:	FBgn0010359	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	266	Identity:	93/266 - (34%)
Similarity:	125/266 - (46%)	Gaps:	36/266 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVI 66
            |..|..|..:||        |..|:...|||||:.:....||||:||.....|.|||||.:|..|
Zfish   277 LGMVTALKCIAC--------GSRPKFSARIVGGNLSAEGQFPWQVSLHFQNEHLCGGSIITSRWI 333

  Fly    67 VTAAHCLQSVSASVLQIRAGSSYWS-SGGVT---------FSVSSFKNHEGYNANTMVNDIAIIK 121
            :|||||:..:        |...||. ..|:|         |:|.....|..|....:.:|||::|
Zfish   334 LTAAHCVYGI--------AYPMYWMVYAGLTELPLNAVKAFAVEKIIYHSRYRPKGLDHDIALMK 390

  Fly   122 INGALTFSSTIKAIGLASSNP--ANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASST 184
            :...|||:..::.|.|.:...  .:|....:||||....|..:..|| ...:|.::|...| |..
Zfish   391 LAQPLTFNGMVEPICLPNFGEQFEDGKMCWISGWGATEDGGDASVSQ-HCASVPLISNKAC-SQP 453

  Fly   185 YGYGSQIRSTMICAA--ASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVA 243
            ..|...:.:.||||.  ..|.|:|||||||||.    |...|||..|||.|||..|.||||..:.
Zfish   454 EVYQGYLTAGMICAGYLDGGTDSCQGDSGGPLACEDSSIWKLVGATSWGQGCAEKNKPGVYTRIT 518

  Fly   244 ALRSWV 249
            ...:|:
Zfish   519 QSLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	85/236 (36%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	6/22 (27%)
		Tryp_SPc	298..525	CDD:238113	85/237 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910