Protein Alignment thetaTry and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 82/247 - (33%)
• Similarity: 131/247 - (53%)
• Gaps: 28/247 - (11%)

  Fly    33 GRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHC-LVGRKVSKVF----VRLGS 92
            ||||||...:....|:||||...: :|.|||:||:...|:||||| .|.|:  ||.    |..|:
Human   324 GRIVGGALASDSKWPWQVSLHFGT-THICGGTLIDAQWVLTAAHCFFVTRE--KVLEGWKVYAGT 385

  Fly    93 TLYNEGGIVVAVRELAYNEDYNSKTMEYDVGILKLDEKVKETENIR--YIELATETPPTGTTAVV 155
            :..::.....::.|:..|.:|..:..:||:.:::|.:.:..:.:|.  .:.:..:|.....|..:
Human   386 SNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWI 450

  Fly   156 TGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCASDEYKYGEIIYDS-----MVCAYEKK--KDACQ 213
            ||:|........|.| .|:||.||::|:|.|  ::|    ::|||     |:||.:.:  :|:||
Human   451 TGFGKTRETDDKTSP-FLREVQVNLIDFKKC--NDY----LVYDSYLTPRMMCAGDLRGGRDSCQ 508

  Fly   214 GDSGGPLAVGNT----LVGIVSWGYACASNLLPGVYSDVPALRKWILNASET 261
            |||||||.....    |.|:.|||..|.....||||:.|..:..||.:..|:
Human   509 GDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	78/238 (33%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747
		Tryp_SPc	325..554	CDD:214473	78/238 (33%)