DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment thetaTry and prss60.1

DIOPT Version :9

Sequence 1:	NP_523693.1	Gene:	thetaTry / 36218	FlyBaseID:	FBgn0011555	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	263	Identity:	95/263 - (36%)
Similarity:	133/263 - (50%)	Gaps:	19/263 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTK-SGSHFCGGSLINE 68
            :.||:|:....:.....|::   |.  ..|||||.:...|:.|:||||.:. .|.|||||||||.
Zfish     9 LALLLCVQGSHSQLNVCGLA---PL--NNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINS 68

  Fly    69 DTVVTAAHCLVGRKVSKVFVRLGSTL---YNEGGIVVAVRELAYNEDYNSKTMEYDVGILKLDEK 130
            :.|:||||||.....|.:.|.||.|.   .|...|...|..:..:..||:.|.|.|:.:|.|...
Zfish    69 EWVLTAAHCLPRITTSSLLVFLGKTTQQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLSSA 133

  Fly   131 VKETENIRYIELATETP--PTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCASDEYKY 193
            |..:..||.:.||.:..  |.||::.:||||:......:..|..|||..:.:|....|  :....
Zfish   134 VTFSNYIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQC--NALLG 196

  Fly   194 GEIIYDSMVCA--YEKKKDACQGDSGGPLAVGNTLV----GIVSWGYACASNLLPGVYSDVPALR 252
            ...:.::|:||  .:..:|.||||||||:.....||    ||.||||.||....||||:.|...:
Zfish   197 SGSVTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQ 261

  Fly   253 KWI 255
            .||
Zfish   262 SWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	88/232 (38%)
thetaTry	NP_523693.1	Tryp_SPc	35..255	CDD:238113	87/231 (38%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	88/232 (38%)
		Tryp_SPc	34..267	CDD:238113	89/233 (38%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910