Protein Alignment thetaTry and ST14

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_068813.1
• Gene: ST14 / 6768
• HGNCID: 11344
• Length: 855
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 90/277 - (32%)
• Similarity: 130/277 - (46%)
• Gaps: 35/277 - (12%)

  Fly     9 VCLAVGS-ACAGTVGVSNGD----------PFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCG 62
            :||:.|: .|.|....|:|.          .|.|:.|:|||.|...|..|:||||......|.||
Human   578 LCLSKGNPECDGKEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICG 642

  Fly    63 GSLINEDTVVTAAHCLV---GRKVS-----KVFVRLGSTLYNEGGIVV--AVRELAYNEDYNSKT 117
            .|||:.:.:|:||||.:   |.:.|     ..|:.|..........|.  .::.:..:..:|..|
Human   643 ASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFT 707

  Fly   118 MEYDVGILKLDEKVKETENIRYIEL--ATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNI 180
            .:||:.:|:|::..:.:..:|.|.|  |:...|.|....|||||...|.....|  .||:..:.:
Human   708 FDYDIALLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGAL--ILQKGEIRV 770

  Fly   181 VDWKTCASDEYKYGEIIYDSMVCA--YEKKKDACQGDSGGPL----AVGNTL-VGIVSWGYACAS 238
            ::..||   |....:.|...|:|.  .....|:|||||||||    |.|... .|:||||..||.
Human   771 INQTTC---ENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQ 832

  Fly   239 NLLPGVYSDVPALRKWI 255
            ...||||:.:|..|.||
Human   833 RNKPGVYTRLPLFRDWI 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	79/239 (33%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		SEA	88..>162	CDD:460188
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060	7/23 (30%)
		Tryp_SPc	615..852	CDD:238113	80/240 (33%)