Protein Alignment thetaTry and PRSS22

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 91/264 - (34%)
• Similarity: 137/264 - (51%)
• Gaps: 32/264 - (12%)

  Fly    11 LAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAA 75
            :.|..||        |.| ::..|:|||||:|....|:.||:| |:|:|.|.|||:....|:|||
Human   143 IPVPPAC--------GKP-QQLNRVVGGEDSTDSEWPWIVSIQ-KNGTHHCAGSLLTSRWVITAA 197

  Fly    76 HCLVGRKVSKVF---VRLGS-TLYNEG--GIVVAVRELAYNEDYNSKTME-YDVGILKLDEKVKE 133
            ||... .::|.:   |.||: .|.|.|  ...|.|..:..:..|:.|... .|:.:::|:..::.
Human   198 HCFKD-NLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQF 261

  Fly   134 TENIRYI---ELATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCASDEYK--- 192
            :|.:..|   :.:...|| .|...::||||......:..|:|||::.|.|:|.:.|:...::
Human   262 SERVLPICLPDASIHLPP-NTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAG 325

  Fly   193 YGEIIYDSMVCA--YEKKKDACQGDSGGPLAV----GNTLVGIVSWGYACASNLLPGVYSDVPAL 251
            .|.|..| |:||  .|.::|||.|||||||..    ...|.||:|||..||....||||..:.|.
Human   326 QGPITED-MLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAH 389

  Fly   252 RKWI 255
            |.|:
Human   390 RSWV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	85/239 (36%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	85/240 (35%)