Protein Alignment thetaTry and CELA2A

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_254275.1
• Gene: CELA2A / 63036
• HGNCID: 24609
• Length: 269
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 96/277 - (34%)
• Similarity: 135/277 - (48%)
• Gaps: 46/277 - (16%)

  Fly     6 VLLVCLAVGSACAGTVGVSNGDPF--EREGRIVGGEDTTIGAHPYQVSLQTKSGS---HFCGGSL 65
            :||..|..|:       :|.|||.  ....|:||||:....:.|:|||||..|..   |.|||||
Human     5 LLLSTLVAGA-------LSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSL 62

  Fly    66 INEDTVVTAAHCLVGRKVSKVFVRLG-STLY--NEGGIVVAVRELAYNEDYNSKTME--YDVGIL 125
            |....|:|||||:...:..:  |.|| ..||  ..|.:.|:|.::..::|:||..:.  .|:.:|
Human    63 IANSWVLTAAHCISSSRTYR--VGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALL 125

  Fly   126 KLDEKVKETENIRYIELATETPPTGT------TAVVTGWGSKCYFWCMT---LPKTLQEVYVNIV 181
            ||...|..|:.|:...|    ||.||      ...|||||.     ..|   :|..||:..:.:|
Human   126 KLANPVSLTDKIQLACL----PPAGTILPNNYPCYVTGWGR-----LQTNGAVPDVLQQGRLLVV 181

  Fly   182 DWKTCASDEYKYGEIIYDSMVCA-YEKKKDACQGDSGGPL----AVGNTLV-GIVSWGYACASNL 240
            |:.||:|..: :|..:..||:|| .:....:|.|||||||    :.|...| ||||:|.....|.
Human   182 DYATCSSSAW-WGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNY 245

  Fly   241 L--PGVYSDVPALRKWI 255
            .  |.|::.|.....||
Human   246 YHKPSVFTRVSNYIDWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	86/245 (35%)
CELA2A	NP_254275.1	Tryp_SPc	29..265	CDD:238113	87/246 (35%)