Protein Alignment thetaTry and KLK10

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_002767.2
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 75/267 - (28%)
• Similarity: 109/267 - (40%)
• Gaps: 67/267 - (25%)

  Fly    12 AVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAH 76
            |.||.||.                        |:.|:||||......| |.|.|:::..|:||||
Human    47 AYGSPCAR------------------------GSQPWQVSLFNGLSFH-CAGVLVDQSWVLTAAH 86

  Fly    77 C----------------LVGRKVSKVFVRLGSTLYNEGGIVVAVRELAYNEDYNSKTMEYDVGIL 125
            |                |.|.::.:....:....|::|...:..|          :|.|:|:.:|
Human    87 CGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPR----------RTDEHDLMLL 141

  Fly   126 KLDEKVKETENIRYIELATETPPTGTTAVVTGWGSKC-----YFWCMTLPKTLQEVYVNIVDWKT 185
            ||...|.....:|.::|.......|....|.|||:..     |      .|.|....:.|:..|.
Human   142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKY------NKGLTCSSITILSPKE 200

  Fly   186 CASDEYKYGEIIYDSMVCA-YEKKKDACQGDSGGPLAVGNTLVGIVSWG-YACASNLLPGVYSDV 248
            |   |..|..::.::|:|| .::.:|.||.||||||....||.||:||| |.|.|...|.||:.:
Human   201 C---EVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQI 262

  Fly   249 PALRKWI 255
            .....||
Human   263 CKYMSWI 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	68/243 (28%)
KLK10	NP_002767.2	Tryp_SPc	49..272	CDD:238113	74/265 (28%)