Protein Alignment thetaTry and PRSS8

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 91/270 - (33%)
• Similarity: 133/270 - (49%)
• Gaps: 22/270 - (8%)

  Fly     5 VVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINED 69
            |.:|:.|.:..:..|..|.........:.||.||.....|..|:|||: |..|.|.|||||::|.
Human    15 VAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSI-TYEGVHVCGGSLVSEQ 78

  Fly    70 TVVTAAHCLVGRKVSKVF-VRLGS---TLYNEGGIVVAVRELAYNEDYNSKTMEYDVGILKLDEK 130
            .|::||||.......:.: |:||:   ..|:|...|..::::..:..|..:..:.|:.:|:|...
Human    79 WVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRP 143

  Fly   131 VKETENIRYIEL--ATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTC------- 186
            :..:..||.|.|  |..:.|.|....|||||.......:..||.||::.|.::..:||
Human   144 ITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNID 208

  Fly   187 ASDEYKYGEIIYDSMVCA--YEKKKDACQGDSGGPLAVGNT----LVGIVSWGYACASNLLPGVY 245
            |..|..:  .:.:.||||  .|..||||||||||||:....    |.||||||.||.:...||||
Human   209 AKPEEPH--FVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVY 271

  Fly   246 SDVPALRKWI 255
            :...:...||
Human   272 TLASSYASWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	84/239 (35%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	85/240 (35%)