Protein Alignment thetaTry and KLK7

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 89/257 - (34%)
• Similarity: 141/257 - (54%)
• Gaps: 25/257 - (9%)

  Fly     4 LVVLLVCLAVGSACAGTVGVSNGDPFEREG-RIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLIN 67
            |.:||:.||:.:|         |:  |.:| :|:.|.....|:||:||:|.:.:..| |||.|:|
Human     9 LQILLLSLALETA---------GE--EAQGDKIIDGAPCARGSHPWQVALLSGNQLH-CGGVLVN 61

  Fly    68 EDTVVTAAHCLVGRKVSKVFVRLGS-TLYNEGGIVVAVRELAYNEDYNSKTMEYDVGILKLDEKV 131
            |..|:|||||    |:::..|.||| ||.:.....:...:...:..|:::|...|:.::||:.:.
Human    62 ERWVLTAAHC----KMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQA 122

  Fly   132 KETENIRYIELATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCASDEYKYGEI 196
            :.:..::.:.|.:...|.|||..|:|||:.. ...:|.|..|..|.|.::..:.|..   .|.::
Human   123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTT-SPDVTFPSDLMCVDVKLISPQDCTK---VYKDL 183

  Fly   197 IYDSMVCA--YEKKKDACQGDSGGPLAVGNTLVGIVSWG-YACASNLLPGVYSDVPALRKWI 255
            :.:||:||  .:.||:||.|||||||....||.|:|||| :.|.....||||:.|....|||
Human   184 LENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	78/224 (35%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	78/224 (35%)