Protein Alignment thetaTry and PRSS2

DIOPT Version :9

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 99/276 - (35%)
• Similarity: 138/276 - (50%)
• Gaps: 51/276 - (18%)

  Fly     6 VLLVCLAVGSACAGTVGVSNGDPFEREGRIVGG---EDTTIGAHPYQVSLQTKSGSHFCGGSLIN 67
            :||:...|.:|.|.        ||:.:.:||||   |:.::   ||||||  .||.||||||||:
Human     3 LLLILTFVAAAVAA--------PFDDDDKIVGGYICEENSV---PYQVSL--NSGYHFCGGSLIS 54

  Fly    68 EDTVVTAAHC--------LVGR--KVSKVFVRLGSTLYN----EGG-IVVAVRELAYNEDYNSKT 117
            |..||:|.||        |.||  :..::.||||.  :|    ||. ..:...::..:..|||:|
Human    55 EQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGE--HNIEVLEGNEQFINAAKIIRHPKYNSRT 117

  Fly   118 MEYDVGILKLDEKVKETENIRYIELATETPPTGTTAVVTGWGSKCYFWCMTL------PKTLQEV 176
            ::.|:.::||.........:..|.|.|..|..||.::::|||:       ||      |..||.:
Human   118 LDNDILLIKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGN-------TLSSGADYPDELQCL 175

  Fly   177 YVNIVDWKTCASDEYKYGEIIYDSMVCA--YEKKKDACQGDSGGPLAVGNTLVGIVSWGYACASN 239
            ...::....|   |..|...|.::|.|.  .|..||:||||||||:.....|.|||||||.||..
Human   176 DAPVLSQAEC---EASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQK 237

  Fly   240 LLPGVYSDVPALRKWI 255
            ..||||:.|.....||
Human   238 NRPGVYTKVYNYVDWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	90/246 (37%)
		Tryp_SPc	35..255	CDD:238113	90/245 (37%)
PRSS2	NP_001290343.1	Tryp_SPc	23..253	CDD:214473	90/246 (37%)
		Tryp_SPc	24..256	CDD:238113	92/247 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920