Protein Alignment thetaTry and PROC

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 75/284 - (26%)
• Similarity: 121/284 - (42%)
• Gaps: 58/284 - (20%)

  Fly    17 CAGTVGVSNGDPFER-------------------EGRIVGGEDTTIGAHPYQVSLQTKSGSHFCG 62
            |...|....|.|::|                   :.|::.|:.|..|..|:||.|........||
Human   270 CHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACG 334

  Fly    63 GSLINEDTVVTAAHCLVGRKVSKVFVRLGS---TLYNEGGIVVAVRELAYNEDYNSKTMEYDVGI 124
            ..||:...|:|||||:...|  |:.||||.   ..:.:..:.:.::|:..:.:|:..|.:.|:.:
Human   335 AVLIHPSWVLTAAHCMDESK--KLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIAL 397

  Fly   125 LKLDEKVKETENIRYIEL------ATETPPTGTTAVVTGWG-----------SKCYFWCMTLPKT 172
            |.|.:....::.|..|.|      ..|....|...:|||||           ::.:        .
Human   398 LHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTF--------V 454

  Fly   173 LQEVYVNIVDWKTCASDEYKYGEIIYDSMVCA--YEKKKDACQGDSGGPLAVG--NT--LVGIVS 231
            |..:.:.:|....|:.   ....::.::|:||  ...::|||:||||||:...  .|  |||:||
Human   455 LNFIKIPVVPHNECSE---VMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVS 516

  Fly   232 WGYACASNLLPGVYSDVPALRKWI 255
            ||..|......|||:.|.....||
Human   517 WGEGCGLLHNYGVYTKVSRYLDWI 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	68/246 (28%)
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251	75/284 (26%)
		Tryp_SPc	308..543	CDD:238113	69/246 (28%)