DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment thetaTry and prss60.2

DIOPT Version :9

Sequence 1:	NP_523693.1	Gene:	thetaTry / 36218	FlyBaseID:	FBgn0011555	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	279	Identity:	102/279 - (36%)
Similarity:	139/279 - (49%)	Gaps:	39/279 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHRL----VVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQT-KSGSHF 60
            |.||    :.||:|:. ||  ...:.|....|.  ..|||||.:...|:.|:|||||: :.|.||
Zfish     1 MWRLTCATLTLLICVK-GS--LSQLNVCGQAPL--NSRIVGGVNAPEGSWPWQVSLQSPRYGGHF 60

  Fly    61 CGGSLINEDTVVTAAHCLVGRKVSKVFVRLG----------STLYNEGGIVVAVRELAYNEDYNS 115
            ||||||:.:.|:||||||.|...|.:.|.||          .|..|...|:|       :..|||
Zfish    61 CGGSLISSEWVLTAAHCLPGVSESSLVVYLGRRTQQGVNTHETSRNVAKIIV-------HSSYNS 118

  Fly   116 KTMEYDVGILKLDEKVKETENIRYIELATETP--PTGTTAVVTGWGSKCYFWCMTLPKTLQEVYV 178
            .|.:.|:.:|:|...|...:.||.:.||.:..  ..||::.:||||.......:..|..|||..:
Zfish   119 NTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTSSWITGWGDVQAGVNLPAPGILQETMI 183

  Fly   179 NIVDWKTCASDEYKYGE-IIYDSMVCAYEKK--KDACQGDSGGPLAVGNTLV----GIVSWGYAC 236
            .:|....|.:   :.|. .:.::|:||...|  ||.||||||||:......|    ||.||||.|
Zfish   184 PVVANDRCNA---QLGSGTVTNNMICAGLAKGGKDTCQGDSGGPMVTRLCTVWIQAGITSWGYGC 245

  Fly   237 ASNLLPGVYSDVPALRKWI 255
            |....||||:.|...:.||
Zfish   246 ADPNSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	90/240 (38%)
thetaTry	NP_523693.1	Tryp_SPc	35..255	CDD:238113	89/239 (37%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	90/240 (38%)
		Tryp_SPc	34..267	CDD:238113	91/241 (38%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910