DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment thetaTry and Prss53

DIOPT Version :9

Sequence 1:	NP_523693.1	Gene:	thetaTry / 36218	FlyBaseID:	FBgn0011555	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	82/317 - (25%)
Similarity:	125/317 - (39%)	Gaps:	90/317 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINED 69
            |:::..|.......|..|  .|.|..:||..:.||      .|:|.|:: :.|.|.|.|||:.:.
  Rat    15 VIVIEGLQAAQRACGQRG--PGPPEPQEGNTLPGE------WPWQASVR-RQGVHICSGSLVADT 70

  Fly    70 TVVTAAHC---LVGRKVSKVFVRLGSTLYNE----GGIVVAVRELAYNEDYNSKTMEYDVGILKL 127
            .|:|||||   :...::|...|.||| |..|    |...|.|..|...:.||..:...|:.:|:|
  Rat    71 WVLTAAHCFEKMATAELSSWSVVLGS-LKQEGLSPGAEEVGVAALQLPKAYNHYSQGSDLALLQL 134

  Fly   128 DEKVKETENIRYIELATETP----PTGTTAVVTGW------GSKC-------------------Y 163
                  |..|.:..|....|    |.|.:...|||      |..|                   .
  Rat   135 ------THPIVHTTLCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQTGSVLTVLALC 193

  Fly   164 FWCMT--------LP--KTLQEVYVNIVDWKTCASDEYKYGEIIYD-------------SMVC-- 203
            ..|::        ||  :||:.:.:.::...||        ..:|:             .|:|
  Rat   194 SHCVSELDSTLSPLPVSRTLRNLRLRLISRPTC--------NCLYNRLHQRLLANPARSGMLCGG 250

  Fly   204 AYEKKKDACQGDSGGPLAV----GNTL-VGIVSWGYACASNLLPGVYSDVPALRKWI 255
            |....:..||||||||:..    |:.: |||:|:...||....|.:.:|:.|...|:
  Rat   251 AQPGVQGPCQGDSGGPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSSWL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	73/286 (26%)
thetaTry	NP_523693.1	Tryp_SPc	35..255	CDD:238113	73/285 (26%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	74/285 (26%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343300
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030