DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment thetaTry and Prss36

DIOPT Version :9

Sequence 1:	NP_523693.1	Gene:	thetaTry / 36218	FlyBaseID:	FBgn0011555	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	86/265 - (32%)
Similarity:	123/265 - (46%)	Gaps:	26/265 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SACAGTVG----VSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAA 75
            ||.:.|.|    :..|.| |...|||||.|...|..|:||||. ..|.|.||||||....|::||
  Rat    36 SAVSPTQGEFEDLDCGRP-EPSSRIVGGSDAHPGTWPWQVSLH-HGGGHICGGSLIAPSWVLSAA 98

  Fly    76 HCLVG----RKVSKVFVRLGSTLYN---EGGIVVAVRELAYNEDYNSKTMEYDVGILKLDEKVKE 133
            ||.|.    ....:..|.||....:   ||..:.:|..:...::|:...:..|:.:|:|....|.
  Rat    99 HCFVTNGTLEPADEWSVLLGVHSQDGPLEGAHMRSVATILVPDNYSRVELGADLALLRLASPAKL 163

  Fly   134 TENIRYIEL--ATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCASDEYKYGEI 196
            ..:::.:.|  |:.....||....||||.......:.:|..||||.:.::....|.....:.|..
  Rat   164 GPSVKPVCLPRASHLFAHGTACWATGWGDVQESDPLPVPWVLQEVELKLLGETACQCLYSRPGPF 228

  Fly   197 -----IYDSMVCA-Y-EKKKDACQGDSGGPLAVGN----TLVGIVSWGYACASNLLPGVYSDVPA 250
                 :...|:|| | |.::|.|||||||||...:    .|.||.|:|:.|.....|||::.|..
  Rat   229 NLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAH 293

  Fly   251 LRKWI 255
            ...||
  Rat   294 YESWI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	77/240 (32%)
thetaTry	NP_523693.1	Tryp_SPc	35..255	CDD:238113	76/239 (32%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	78/241 (32%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343272
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940