DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment thetaTry and prss27

DIOPT Version :9

Sequence 1:	NP_523693.1	Gene:	thetaTry / 36218	FlyBaseID:	FBgn0011555	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	289	Identity:	103/289 - (35%)
Similarity:	146/289 - (50%)	Gaps:	39/289 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHRLVVLLVC----LAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFC 61
            |.|::.||:.    .|:.:.|        |.|...: |||||.:...|..|:|||: ....||.|
Frog   391 MLRIISLLLAGFAVTAISTGC--------GQPAFSD-RIVGGNNAVFGEWPWQVSI-VYQNSHIC 445

  Fly    62 GGSLINEDTVVTAAHCLV-GRKVSKVFVRLGS-TLYN--EGGIVVAVRELAYNEDYNSKTMEYDV 122
            ||||::.:.||:||||.. ..|:..:.|.||. .|.|  ...:::.|:.:.....|..:....|:
Frog   446 GGSLVSSNWVVSAAHCFPRSYKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDI 510

  Fly   123 GILKLDEKVKETENIR--YIELATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKT 185
            .:::::..|..:..|.  .|.|..|..|:|....|||||:......::.|..||||.|.:|:..:
Frog   511 AMVEMESPVTYSSYILPICIPLTNEDFPSGKMCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASS 575

  Fly   186 CASDEYKYG-------EIIYDSMVCA-Y-EKKKDACQGDSGGPLAV--GN--TLVGIVSWGYACA 237
            | ...|.|.       ::::|.|:|| | |.:|||||||||||||.  ||  .|.||||||..||
Frog   576 C-DTMYHYNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACKSGNYWFLTGIVSWGDGCA 639

  Fly   238 SNLLPGVYSDVPALRKWI-----LNASET 261
            ....||||:.|.:...||     ||.|.|
Frog   640 QPNRPGVYTKVSSFSSWINQYLVLNVSVT 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	89/239 (37%)
thetaTry	NP_523693.1	Tryp_SPc	35..255	CDD:238113	88/238 (37%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	90/240 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910