Protein Alignment thetaTry and ACR

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 84/297 - (28%)
• Similarity: 122/297 - (41%)
• Gaps: 66/297 - (22%)

  Fly     4 LVVLLVCLAV--GSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQ----TKSGSHFCG 62
            |:||.|.:..  .:.|.|..|:......:...|||||:....||.|:.||||    .....|.||
Human    10 LLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCG 74

  Fly    63 GSLINEDTVVTAAHCLVGRKVSKVFVRLGSTLYNEGGIVVAVRELAY------------------ 109
            |||:|...|:|||||.||:           ...::..:|...:|:.|
Human    75 GSLLNSRWVLTAAHCFVGK-----------NNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKI 128

  Fly   110 --NEDYNSKTMEYDVGILKLDEKVKETENIRYI------ELATETPPTGTTAVVTGWG---SKCY 163
              :|.|||.|...|:.::::...:...   |:|      ......|....:..|.|||   .|.
Human   129 IIHEKYNSATEGNDIALVEITPPISCG---RFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKA- 189

  Fly   164 FWCMTLPK---TLQEVYVNIVDWKTCASDEYKYGEIIYDSMVCAYEKKK-DACQGDSGGPLAVGN 224
                  |:   .|.|..|:::|...|.|.::..|.:...::...|...| |.|||||||||...:
Human   190 ------PRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKD 248

  Fly   225 T------LVGIVSWGYACASNLLPGVYSDVPALRKWI 255
            :      :|||.|||..||....||:|:.......||
Human   249 SKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	75/263 (29%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	75/263 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421