Protein Alignment thetaTry and KLK14

DIOPT Version :10

• Sequence 1: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 89/276 - (32%)
• Similarity: 136/276 - (49%)
• Gaps: 45/276 - (16%)

  Fly     4 LVVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHF-CGGSLIN 67
            :.:||..|.|       :.::.....|.|.:|:||...|..:.|:|.:|.......| |||:|::
Human     1 MFLLLTALQV-------LAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLS 58

  Fly    68 EDTVVTAAHCLVGRKVSKVFV------RLGSTLYNEGGIVVAVRELAYNEDYNSKTMEYDVGILK 126
            ...|:|||||  ||.:.:|.:      |..:|..    ::..||::.: .:|||:|.:.|:.:|:
Human    59 GQWVITAAHC--GRPILQVALGKHNLRRWEATQQ----VLRVVRQVTH-PNYNSRTHDNDLMLLQ 116

  Fly   127 LDEKVKETENIRYIELATETPPTGTTAVVTGWGSKCYFWCMTL-------PKTLQEVYVNIVDWK 184
            |.:..:....:|.||:.......||:..|:|||        |:       |.:||.|.:||...:
Human   117 LQQPARIGRAVRPIEVTQACASPGTSCRVSGWG--------TISSPIARYPASLQCVNINISPDE 173

  Fly   185 TCASDEYKYGEIIYDSMVCA--YEKKKDACQGDSGGPLAVGNTLVGIVSWGY-ACASNLLPGVYS 246
            .|   :..|...|...||||  .:..||:|||||||||.....|.|:||||. .||....||||:
Human   174 VC---QKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYT 235

  Fly   247 DVPALRKWILNASETL 262
            ::...|.||   .||:
Human   236 NLCKYRSWI---EETM 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	79/237 (33%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	81/242 (33%)