DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment thetaTry and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_523693.1	Gene:	thetaTry / 36218	FlyBaseID:	FBgn0011555	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	94/249 - (37%)
Similarity:	128/249 - (51%)	Gaps:	39/249 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 RIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHCLVGR------KVSKVFVRLGS 92
            ::.||:|...|..|:|.||| ::..|.||.:||:...::|||||.|..      |||..|
  Rat   186 KVAGGQDAEEGEWPWQASLQ-QNNVHRCGATLISNSWLITAAHCFVRSANPKDWKVSFGF----- 244

  Fly    93 TLYNEGGIVVAVRELAYNEDYNSKTMEYDVGILKLDEKVKETENIRYIEL--ATETPPTGTTAVV 155
             |.::.....||:.:..:|:|:......|:.:::|...|....|||...|  ||:..|..:..||
  Rat   245 -LLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVV 308

  Fly   156 TGWGSKCYFWCMTL------PKTLQEVYVNIVDWKTCASDEYKYGEIIYDSMVCA--YEKKKDAC 212
            ||||        ||      |..||:..|.|:|.|||.|.: .||.:|...|:||  .|.:.|||
  Rat   309 TGWG--------TLKSDGDSPNILQKGRVKIIDNKTCNSGK-AYGGVITPGMLCAGFLEGRVDAC 364

  Fly   213 QGDSGGPLAVGNT-----LVGIVSWGYACASNLLPGVYSDVPALRKWILNASET 261
            ||||||||...::     |.||||||..||....||||:.|...|.||  :|:|
  Rat   365 QGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWI--SSKT 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	90/241 (37%)
thetaTry	NP_523693.1	Tryp_SPc	35..255	CDD:238113	90/240 (38%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	90/241 (37%)
		Tryp_SPc	187..415	CDD:238113	92/245 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920